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Alcohol and Its Interactions

Alcohol is one of the few mind-altering drugs that has defined effects on behavior. Its interaction with borderline personality disorder is particularly significant.

  • Chemical formula: C₂H₅OH (Ethanol)
  • Produced by the fermentation of sugar (conversion by yeast into ethanol and carbon dioxide)
  • A cellular toxin that attacks every single cell in the body
  • Crosses the blood-brain barrier without difficulty
  • Dissolves only in water (water-containing body parts)

Alcohol directly interferes with the brain’s biochemical metabolism:

  1. First, the neocortex (cerebrum) is paralyzed — cognitive inhibitions are overridden
  2. The limbic system is activated — where emotions and reward systems reside
  3. Result: Disinhibition; feelings, fears, and repressed content that are normally kept in check come to the surface

Alcohol brings the deepest inner self to the surface and makes a person more unpredictable than any other drug.

Caution with diagnosis: Alcohol abuse can produce symptoms that resemble borderline personality disorder. This is also a common mistake among doctors who diagnose borderline when “only” alcohol abuse is present.

  • Alcohol intensifies the existing emotional state
  • It brings underlying feelings and emotions to the surface
  • A two-phase poison in depression: First it lifts the mood, then the original state becomes even worse

Values refer to a male, 67 kg, without alcohol tolerance:

BAC (‰)Effect
up to 0.3Usually no effect
up to 0.6Warmth, relaxation, euphoria, mild motor impairment
up to 0.9Disinhibited behavior, exaggerated emotionality, onset of intoxication, distorted perception
up to 1.2Erratic behavior, staggering, slurred speech
up to 2.5Severe perceptual and motor disturbances, possible loss of consciousness
above 2.5Worsening of all symptoms
4-5.0Total stupor or death
(Amount consumed in grams of alcohol) ÷ (Body weight × 0.7) = BAC in ‰

Rules of thumb:

  • Drinking more slowly per hour: minus 0.1 ‰
  • Drinking faster per hour: plus 0.1 ‰
  • Per 10 kg more body weight: minus 0.1 ‰
  • Per 10 kg less body weight: plus 0.1 ‰

Metabolism: Men metabolize 0.1 ‰ per hour, women 0.08 ‰.

BeverageVol%AmountAlcohol (g)
Beer5%0.5 l20g
Wine10%0.125 l10-13g
Sparkling wine12%0.1 l10g
Liqueur30%4 cl9g
Grain spirit32%4 cl10g
Vodka, Gin40%4 cl13g
  • Sex (male/female)
  • Eating habits (bulimia, anorexia)
  • What was eaten and when
  • Drinking speed and habits
  • Psychological state (stress)
  • General health (illness, menstruation)
  • Use of medications

According to research, those who later end up in abuse or addiction initially use alcohol as self-medication — to combat inner emptiness, anger, rage, helplessness, fear, depression, melancholy, or to quickly dampen emotions.

  • Physical dependence: Treatment is not difficult, usually takes just a few weeks
  • Psychological dependence: Extremely difficult, requires at least 2 years and identifying the underlying causes (e.g., ADHD, borderline personality disorder)

It is useless to treat someone for alcohol addiction without finding and treating the underlying problem.

Clearly yes.

  • 1 gram of alcohol = 29 kJ of energy
  • 1 liter of beer = 2000 kJ (20% of a man’s daily requirement)
  • The excess energy is stored as fat

The person with alcoholism is stigmatized because it is supposedly “just a matter of willpower.” This is wrong. Medication abuse is also viewed differently by society — because it is invisible.

We often say: “There’s an alcoholic, disheveled on a park bench.” But that is only the bitter end that we get to see.

No one who became addicted or engaged in substance abuse ever raised their hand and shouted: “I want this.” It takes external circumstances for that. The drug only accelerates everything.

Childhood, mother, father, life, your circumstances — and ultimately the insurmountable, unprocessed pain within.

People who manage to break free from this cycle have my deepest respect. They are wonderful people. People who achieve this can achieve anything.


And one thing we should never forget: It can happen to anyone. Too many have said “it could never happen to me!”